The role of Power Doppler ultrasonography in comparison with biological markers in the evaluation of disease activity in Juvenile Idiopathic Arthritis.
Source: Medical Ultrasonography. May, Vol. Methods: Forty hospital visits were studied comprising 32 patients with JIA, during one year of follow-up.
Each patient underwent clinical, laboratory and ultrasound PDUS evaluation. The physician global assessment score on the visual analog scale PhGA was used as a standard for assessing disease activity, based on previous studies. The PDUS signal was scored according to a semiquantitative four grade scale Conclusion: Laboratory tests used today are not sufficiently sensitive for the prediction of active disease.
PDUS assessment of synovial vascularisation is a technique with good sensitivity and specificity, thus it may be a beneficial criteria for evaluating disease activity in JIA, completing conventional clinical examination.
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Doi pacienţi cu artrită juvenilă idiopatică au dezvoltat o infecţie cu varicelă însoţită de semne şi simptome de meningită aseptică, care s- a remis fără sechele. The types and proportion of adverse events in juvenile idiopathic arthritis patients were similar to those seen in trials of Enbrel in adult patients with rheumatoid arthritis, and the majority were mild.
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